Objective?To explore the risk factors and clinical characteristics of recurrence of acute pancreatitis(AP).Methods?Clinical data of 353 AP patients were collected and the patients were divided into the recurrence group (96 cases) and the non-recurrence group (257 cases) according to whether or not there was a recurrence.The etiology(including cholangiogenesis,hyperlipidemia,alcohol and other causes) and clinical data (including general data,disease history and c-reactive protein test results) of the two groups were compared,and risk factors for AP recurrence were analyzed.Results?The proportion of hyperlipidemic AP patients in the recurrence group was significantly higher than that in the non-recurrence group(P<0.05).The length of hospital stay in the recurrence group was significantly lower than that in the non-recurrence group(P<0.05).Multivariate?logistic?regression analysis showed that hyperlipidemia was a risk factor for recurrence of AP(OR=3.074，95%CI?1.728-5.469，P<0.01).Conclusion?The mean hospital stay of patients with recurrent AP is lower than that of patients without recurrent AP,and hyperlipidemia was a risk factor for recurrent AP.